𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Wilms' tumours with intracaval involvement

✍ Scribed by Martínez-Ibáñez, Vicente; de Toledo, José Sánchez; De Diego, Marta; Castellote, Amparo; Sábado, Constantino; Javier, Germán; Marqués, Alfredo; Boix-Ochoa, José


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
379 KB
Volume
26
Category
Article
ISSN
0098-1532

No coin nor oath required. For personal study only.

✦ Synopsis


Since Gross established the basic rules for nephrectomy in Wilms' tumour (WT) in 1953, the management of nephroblastoma has been more straightforward. However, some cases with intravascular involvement, currently detected by ultrasound (US), may represent a daunting challenge for the surgeon. Inferior vena cava with tumour thrombus induced by W l can be asymptomatic and, if undetected, can contribute to poorer prognosis for two main reasons: possible neoplastic cells inside the thrombus and higher morbidity risk of surgery. From 1979 to 19!23,81 WT were studied by routine US. lntracaval thrombosis was diagnosed in four (5%), in one of which the thrombus extended to the right atrium. In our experience, the surgical strategy in each of the four cases (100% survival) depended on the length of the thrombus and whether or not it infiltrated the vena cava wall. If the thrombus can be easily removed: complete resection. However, in cases of atrial thrombus, and more particularly if the thrombus in- volves the intima, we suggest the thrombus not be touched since the problem may be solved by preoperative and postoperative chemotherapy. Thus the favourable prognosis would be maintained and superfluous risky surgery avoided.


📜 SIMILAR VOLUMES


Tumour-specific antibodies reactive with
✍ Shant Kumar; Madhav Waghe; Geoffrey Taylor 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 French ⚖ 373 KB

## Abstract Tumour‐specific antibodies directed against membrane antigens were demonstrated by immuno‐fluorescence in three of 45 patients with Wilms' tumour. Antibody capable of collaborating with K cells to kill Wilms' tumour was present in two additional patients. No patient exhibited both membr

Non-organ-specific and tumour-specific a
✍ Shant Kumar; Geoffrey Taylor 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 693 KB

## Abstract Sera from groups of children with Wilms' tumour, with non‐renal solid tumours, and from control children were studied by immunofluorescence and by absorption techniques. A high proportion of sera from both tumour groups contained non‐organ‐specific auto‐antibodies. Three of the 45 sera

Screening for wilms' tumour in patients
✍ Craft, Alan W. ;Parker, Louise ;Stiller, Charles ;Msc, Michael Cole 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB

The role of screening for early detection of Wilms' tumour (W) in patients with aniridia (A), Beckwith-Weidemann syndrome (BWS) and hemihypertrophy (HH) has been explored. Of the 1,622 Wilms' tumour patients registered with the National Childhood Cancer Registry from 1971 to 1991, 41 were recorded a

Regulation of the Wilms' tumour suppress
✍ Ward, Andrew; Dutton, James R. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 1 views

Antisense transcripts are typically associated with the down-regulation of gene expression. In this issue, Moorwood et al. present evidence that an antisense RNA can enhance expression of the Wilms' tumour suppressor locus WT1. We suggest that the unusual function of the WT1 antisense RNA might rela

Homozygous intragenic deletion in the WT
✍ Elizabeth M. Algar; Mark T. Kenney; Lisa A. Simms; Shirley I. Smith; Yoshiki Kid 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 859 KB

Communicated by R. G. H. Cotton We have examined a panel of 21 sporadic Wilms' tumours for rearrangements in the Wilms' tumour suppressor gene, WT1. In one tumour with specific allele loss in chromosome llp13, a homozygous deletion in the 3' end of the gene, encompassing exon 10 and the 3' untransla