## Abstract Sera from groups of children with Wilms' tumour, with non‐renal solid tumours, and from control children were studied by immunofluorescence and by absorption techniques. A high proportion of sera from both tumour groups contained non‐organ‐specific auto‐antibodies. Three of the 45 sera
Tumour-specific antibodies reactive with cell-surface antigens in children with wilms' tumour
✍ Scribed by Shant Kumar; Madhav Waghe; Geoffrey Taylor
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- French
- Weight
- 373 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
Tumour‐specific antibodies directed against membrane antigens were demonstrated by immuno‐fluorescence in three of 45 patients with Wilms' tumour. Antibody capable of collaborating with K cells to kill Wilms' tumour was present in two additional patients. No patient exhibited both membrane immunofluorescence and K‐cell collaborating antibody. Of 27 patients with non‐renal solid tumours and 52 age‐matched controls, none possessed tumour‐specific antibody.
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