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Non-organ-specific and tumour-specific antibodies in children with Wilms' tumour

✍ Scribed by Shant Kumar; Geoffrey Taylor

Publisher
John Wiley and Sons
Year
1975
Tongue
French
Weight
693 KB
Volume
16
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Sera from groups of children with Wilms' tumour, with non‐renal solid tumours, and from control children were studied by immunofluorescence and by absorption techniques. A high proportion of sera from both tumour groups contained non‐organ‐specific auto‐antibodies. Three of the 45 sera in the Wilms' group and one of the 27 sera in the “other” solid tumour group contained antibody reacting with normal kidney cells. Only one of 45 sera in the Wilms' tumour group contained tumour‐specific antibody.

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