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Wild-type p53 activates transcription in vitro

✍ Scribed by Farmer, George; Bargonetti, Jill; Zhu, Hua; Friedman, Paula; Prywes, Ron; Prives, Carol

Book ID: 109781038
Publisher: Nature Publishing Group
Year: 1992
Tongue: English
Weight: 479 KB
Volume: 358
Category: Article
ISSN: 0028-0836
DOI: 10.1038/358083a0

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## Abstract In response to various stresses, p53 is rapidly activated and transcriptionally regulates a number of target genes by which p53 modulates a variety of cellular activities. The transcriptional activity of p53 is delicately regulated by a plethora of cellular factors, independently or syn