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When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly

✍ Scribed by Klaus Turnheim

Book ID
114253935
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
180 KB
Volume
38
Category
Article
ISSN
0531-5565

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Pharmacokinetics and pharmacodynamics of
Pharmacokinetics and pharmacodynamics of the diuretic bumetanide in the elderly*
✍ Oberbauer, Rainer; Krivanek, Peter; Turnheim, Klaus πŸ“‚ Article πŸ“… 1995 πŸ› Nature Publishing Group 🌐 English βš– 896 KB

In a cross-sectional study of the pharmacokinetics and pharmacodynamics of peroral and intravenous bumetanide (0.5 mg, single dose), total and renal clearance of the diuretic was si~ni6cantly lower in elderly persons than in young adults, resulting in higher bumetanide plasma levels in the aged. Non