𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetic and Pharmacodynamic Changes in the Elderly

✍ Scribed by Andrea Hämmerlein, Hartmut Derendorf, Dr David T. Lowenthal


Book ID
119926186
Publisher
Springer International Publishing AG
Year
1998
Tongue
English
Weight
190 KB
Volume
35
Category
Article
ISSN
0312-5963

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✍ Oberbauer, Rainer; Krivanek, Peter; Turnheim, Klaus 📂 Article 📅 1995 🏛 Nature Publishing Group 🌐 English ⚖ 896 KB

In a cross-sectional study of the pharmacokinetics and pharmacodynamics of peroral and intravenous bumetanide (0.5 mg, single dose), total and renal clearance of the diuretic was si~ni6cantly lower in elderly persons than in young adults, resulting in higher bumetanide plasma levels in the aged. Non