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Pharmacokinetic and pharmacodynamic characteristics of trazodone in the elderly.

✍ Scribed by Bayer, AJ (author);Pathy, MS (author);Ankier, SI (author)


Book ID
117943223
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
643 KB
Volume
16
Category
Article
ISSN
0306-5251

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In a cross-sectional study of the pharmacokinetics and pharmacodynamics of peroral and intravenous bumetanide (0.5 mg, single dose), total and renal clearance of the diuretic was si~ni6cantly lower in elderly persons than in young adults, resulting in higher bumetanide plasma levels in the aged. Non