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Well-Ordered Mesoporous Silica Nanoparticles as a Recoverable Catalyst for One-Pot Multicomponent Synthesis of 4H-Chromene Derivatives

✍ Scribed by SARRAFI, Yaghoub; MEHRASBI, Ebrahim; VAHID, Amir; TAJBAKHSH, Mahmood

Book ID: 120290614
Publisher: Elsevier Science
Year: 2012
Weight: 448 KB
Volume: 33
Category: Article
ISSN: 1872-2067
DOI: 10.1016/S1872-2067(11)60423-3

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## Abstract Reaction of an isocyanide with an electron‐poor aromatic aldehyde in the presence of silica nanoparticles (silica NP; __ca.__ 42 nm) proceeds smoothly at room temperature to afford 2‐hydroxyacetamide derivatives in high yields (__Scheme 1__ and __Table 1__).