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A green one-pot multicomponent synthesis of 4H-pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications using silica nanoparticles as reusable catalyst

✍ Scribed by Subhash Banerjee; Alissa Horn; Hari Khatri; Grigoriy Sereda


Book ID
104098949
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
608 KB
Volume
52
Category
Article
ISSN
0040-4039

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Preparation of Silica Nanoparticles from
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## Abstract Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between 6‐formyl‐2,3‐dimethoxybenzoic acid and secondary amines (dibenzyl‐ or benzyl(isopropyl)amine) in the presence of silica nanoparticles (silica NPs, __ca.__ 70β€…nm) proceeds smoothly at room temperature

ChemInform Abstract: Preparation of Sili
✍ Ali Ramazani; Amir Mahyari; Azam Farshadi; Morteza Rouhani πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons βš– 13 KB πŸ‘ 2 views

## Abstract Multicomponent reaction of o‐formylbenzoic acid derivative (I) with secondary amines (III) and isocyanides (II) proceeds smoothly in the presence of silica nanoparticles under neat conditions to give dihydroisoindolone derivatives (IV) in good yields.