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ChemInform Abstract: Preparation of Silica Nanoparticles from Organic Laboratory Waste of Silica Gel HF254 and Their Use as a Highly Efficient Catalyst for the One-Pot Synthesis of 2,3-Dihydro-1H-isoindolone Derivatives.

✍ Scribed by Ali Ramazani; Amir Mahyari; Azam Farshadi; Morteza Rouhani

Publisher: John Wiley and Sons
Year: 2012
Weight: 13 KB
Volume: 43
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201210107

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✦ Synopsis

Abstract

Multicomponent reaction of o‐formylbenzoic acid derivative (I) with secondary amines (III) and isocyanides (II) proceeds smoothly in the presence of silica nanoparticles under neat conditions to give dihydroisoindolone derivatives (IV) in good yields.

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