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Well-Defined N-Heterocyclic Carbene Based Ruthenium Catalysts for Direct Amide Synthesis from Alcohols and Amines

✍ Scribed by Zhang, Yao; Chen, Cheng; Ghosh, Subhash Chandra; Li, Yongxin; Hong, Soon Hyeok


Book ID
121014483
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
840 KB
Volume
29
Category
Article
ISSN
0276-7333

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N-Heterocyclic Carbene Based Ruthenium-C
✍ Chen, Cheng; Zhang, Yao; Hong, Soon Hyeok πŸ“‚ Article πŸ“… 2011 πŸ› American Chemical Society 🌐 English βš– 487 KB

A well-defined N-heterocyclic carbene based ruthenium complex was developed as a highly active precatalyst for the direct amide synthesis from alcohols and secondary amines. Notably, reaction of 1-hexanol and dibenzylamine afforded 60% of the corresponding amide using our catalytic system, while no

Direct Amide Synthesis from Alcohols and
✍ Subhash Chandra Ghosh; Senthilkumar Muthaiah; Yao Zhang; Xiangya Xu; Soon Hyeok πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 208 KB πŸ‘ 1 views

## Abstract Amides are synthesized directly from alcohols and amines in high yields using an __in situ__ generated catalyst from easily available ruthenium complexes such as the (__p__‐cymene)ruthenium dichloride dimer, [Ru(__p__‐cymeme)Cl~2~]~2~, or the (benzene)ruthenium dichloride dimer, [Ru(ben