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Weekly therapy with folinic acid and high-dose 5-fluorouracil 24-hour infusion in previously untreated patients with metastatic colorectal carcinoma

✍ Scribed by Weh, H.J.; Dierlamm, J.; Hossfeld, D.K.

Book ID
122022849
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
280 KB
Volume
30
Category
Article
ISSN
0959-8049

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✍ Tsai-Shen Yang; Kuan-Cheng Hsu; Jy-Ming Chiang; Reiping Tang; Jinn-Shium Chen; C πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 70 KB πŸ‘ 2 views

## BACKGROUND. Reports of in vitro experiments in colorectal carcinoma cells suggest that prolonged cellular exposure to 5-fluorouracil (5-FU) combined with relatively low concentrations of leucovorin (LV) provides optimal enhancement of 5-FU efficacy. In this study, a simplified regimen of weekly