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Weekly continuous infusion of 5-fluorouracil with oral leucovorin in metastatic breast cancer patients with primary resistance to doxorubicin

✍ Scribed by Yago Nieto; Miguel Martín; José Luis Alonso; Antonio Casado; Francisco Ayala; José Antonio López-Martín; Alvaro Rodríguez-Lescure; Eduardo Díaz-Rubio


Book ID
118660929
Publisher
Springer US
Year
1998
Tongue
English
Weight
611 KB
Volume
50
Category
Article
ISSN
0167-6806

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A phase II trial of weekly high dose con
✍ Enrique Aranda; Andrés Cervantes; Javier Dorta; Esperanza Blanco; Carlos Fernánd 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB 👁 2 views

Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer