Weekly Administration of Folic Acid and Epidemiology of Neural Tube Defects
✍ Scribed by Laura E. Martínez de Villarreal; Patricia Arredondo; Ricardo Hernández; Jesús Z. Villarreal
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 264 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1092-7875
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Epidemiologic studies have established clear variations in the occurrence of neural tube defects (NTDs) associated with demographic and other factors. Methods of counting NTD-affected pregnancies and other birth defects rely on multiple sources of information such as hospital records and birth certi
## Abstract ## BACKGROUND: It is well established that women who have had a pregnancy affected by a neural tube defect (NTD) have an elevated risk of a subsequent NTD‐affected pregnancy and that a high dose (4 mg/day) of folic acid taken around the time of conception prevents most recurrences of N
There are many different naturally-occurring forms of folic acid, often referred to collectively as folate. Folic acid (pteroylmonoglutamate) does not occur in food, but is the form of folate in the supplements used in the studies referred to here. Because all forms of folate are metabolically linke