𝔖 Bobbio Scriptorium
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Water-soluble macromolecular fluorogenic substrates for assaying proteinases: Determination of pancreatic elastase activity

✍ Scribed by Fabienne Anjuère; Michel Monsigny; Roger Mayer

Book ID
107718972
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
561 KB
Volume
198
Category
Article
ISSN
0003-2697

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Fluorogenic Substrates Containing 7-Amin
Fluorogenic Substrates Containing 7-Amino-4-methyl-2-quinolinone for Aminopeptidase M, Chymotrypsin, Elastase and Trypsin, Determination of Enzyme Activity
✍ Tzougraki, Chryssa ;Noula, Catherine ;Geiger, Reinhard ;Kokotos, George 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 432 KB

## Abstract Several new fluorogenic substrates for four proteases were synthesized by coupling the highly fluorescent __7__‐amino‐4‐methyl‐2‐quinolinone (AMeq) with appropriate amino acids and peptides. Compounds HCl · H‐Ala‐NH‐Meq (1) and HCl · H‐Leu‐NH‐Meq (2) are substrates for aminopeptidase M,