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A new water-soluble substrate for the determination of trypsin activity

✍ Scribed by P.H. Zassenhaus; K.M. Hanson; R.L. Wolgemuth

Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
465 KB
Volume
76
Category
Article
ISSN
0003-2697

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✍ Tzougraki, Chryssa ;Noula, Catherine ;Geiger, Reinhard ;Kokotos, George πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 432 KB

## Abstract Several new fluorogenic substrates for four proteases were synthesized by coupling the highly fluorescent __7__‐amino‐4‐methyl‐2‐quinolinone (AMeq) with appropriate amino acids and peptides. Compounds HCl Β· H‐Ala‐NH‐Meq (1) and HCl Β· H‐Leu‐NH‐Meq (2) are substrates for aminopeptidase M,