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von Willebrand factor-cleaving protease activity in congenital thrombotic thrombocytopenic purpura

✍ Scribed by S. L. Allford; P. Harrison; A. S. Lawrie; R. Liesner; I. J. Mackie; S. J. Machin


Book ID
108672473
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
217 KB
Volume
111
Category
Article
ISSN
0007-1048

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## Abstract Decreased von Willebrand factor (VWF)‐cleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (Upshaw‐Schulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we