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ticlopidine-Associated Thrombotic Thrombocytopenic Purpura With an IgG-Type Inhibitor to von Willebrand Factor-Cleaving Protease Activity

✍ Scribed by Yasuhiro Sugio; Takashi Okamura; Kazuya Shimoda; Masanori Matsumoto; Hideo Yagi; Hiromichi Ishizashi; Yoshiyuki Niho; Shoichi Inaba; Yoshihiro Fujimura


Book ID
105675357
Publisher
Carden Jennings Publishing
Year
2001
Tongue
English
Weight
77 KB
Volume
74
Category
Article
ISSN
0925-5710

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## Abstract Decreased von Willebrand factor (VWF)‐cleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (Upshaw‐Schulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we