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Volumes of distribution and mean residence time of drugs with linear tissue distribution and binding and nonlinear protein binding

โœ Scribed by Haiyung Cheng; William R. Gillespie

Book ID
112736798
Publisher
Springer
Year
1996
Tongue
English
Weight
596 KB
Volume
24
Category
Article
ISSN
1573-8744

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๐Ÿ“œ SIMILAR VOLUMES

Mean residence time of drugs administere
Mean residence time of drugs administered non-instantaneously and undergoing linear tissue distribution and reversible metabolism and linear or non-linear elimination from the central compartment
โœ Haiyung Cheng ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 409 KB ๐Ÿ‘ 2 views

Based on disposition decomposition analysis (DDA), equations for the mean residence times (MRT) in the body are derived for a drug and its interconversion metabolite that undergo linear tissue distribution and linear or non-linear elimination from the central compartment after non-instantaneous admi