Successful in vivo NMR spectroscopy requires a combination of techniques to address the problems of volume selection, water suppression, and resolution. All this needs to be done in the very heterogeneous environment found in living organisms. Previously published techniques are used to obtain 'H sp
Volume-selected proton spectroscopy in the human brain
β Scribed by C.C Hanstock; D.L Rothman; T Jue; R.G Shulman
- Publisher
- Elsevier Science
- Year
- 1988
- Weight
- 380 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-2364
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## Abstract Localized proton spectroscopy of the brain was performed on MS patients (__n__ = 18) and the results are compared with those of a control group (__n__ = 17). The experiments were performed in a 1.5βT Siemens Magnetom using the stimulated echo method and selective water suppression. Acqu
In vivo localized proton magnetic resonance spectroscopy (MRS) studies of brain were performed on eighteen normal subjects using the stimulated echo (STE) sequence. The absolute concentrations and proton relaxation times of N-acetyl aspartate (NAA), total creatine (Cr) and choline (Cho) were estimat