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In vivo proton magnetic resonance spectroscopy studies of human brain

โœ Scribed by P.A. Narayana; D. Johnston; D.P. Flamig

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
845 KB
Volume
9
Category
Article
ISSN
0730-725X

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โœฆ Synopsis

In vivo localized proton magnetic resonance spectroscopy (MRS) studies of brain were performed on eighteen normal subjects using the stimulated echo (STE) sequence. The absolute concentrations and proton relaxation times of N-acetyl aspartate (NAA), total creatine (Cr) and choline (Cho) were estimated. The MRS data was quantitatively analyzed for repeatability and intersubject variability. Quantitative analysis indicates excellent spectral repeatability. Significant intersubject variations in [NAA] and [Cr] have been observed while the intersubject variability in [Cho] has been found to be fairly small. Significant intensity distortions have been observed for mixing times longer than 50 msec.

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