𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vivo high-resolution volume-selected proton spectroscopy and T1 measurements in the dog brain

✍ Scribed by Graham J. Galloway; James Field; Stephen E. Rose; Luke J. Haseler; William M. Brooks; Ian M. Brereton; Peter J. Bore; Stuart Crozier; David M. Doddrell

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
406 KB
Volume
9
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Successful in vivo NMR spectroscopy requires a combination of techniques to address the problems of volume selection, water suppression, and resolution. All this needs to be done in the very heterogeneous environment found in living organisms. Previously published techniques are used to obtain 'H spectra from a dog brain, observing metabolites with concentrations below 1 mM. Measurements of spin-lattice relaxation times (T,) are also presented. The 'H relaxation times are long ( T , > 1 .O s) yielding information about the fluidity of the molecular environment. Comments are made concerning the achievable linewidth in vivo and the deficiencies that phase-encoding spectroscopic methods may have in obtaining high-resolution 'H spectra. o 1989 Academic Press, Inc.

πŸ“œ SIMILAR VOLUMES

Localized proton MR spectroscopy of citr
Localized proton MR spectroscopy of citrate in vitro and of the human prostate in vivo at 1.5 T
✍ Fritz Schick; Hilmar Bogers; Siegfried Kurz; Wulf-Ingo Jung; Markus Pfeffer; Pro πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 486 KB πŸ‘ 1 views

## Abstract Citrate is a secretory product of the normal prostate, a lack of citrate in prostate tissue is expected to be pathognomonic for adenocarcinoma. In the present study proton AB‐signal characteristics of citrate at low field strength of 1.5 T were investigated by __volume selective spectro

Quantitative measurements of proton spin
Quantitative measurements of proton spin-lattice (T1) and spin–spin (T2) relaxation times in the mouse brain at 7.0 T
✍ David N. Guilfoyle; Victor V. Dyakin; Jacqueline O'Shea; Gaby S. Pell; Joseph A. πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 382 KB πŸ‘ 1 views

The goal of this work is to provide regional T(1) and T(2) values at a field strength of 7 T for the normal mouse brain at 6 weeks and 1 year old. A novel segmented snapshot FLASH sequence was used to measure T(1) in the hippocampus, corpus callosum, and the retrosplenial granular (RSG) cortex; T(2)

High-resolution T1 and T2 mapping of the
High-resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2
✍ Sean C. L. Deoni; Terry M. Peters; Brian K. Rutt πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 433 KB

## Abstract Variations in the intrinsic __T__~1~ and __T__~2~ relaxation times have been implicated in numerous neurologic conditions. Unfortunately, the low resolution and long imaging time associated with conventional methods have prevented __T__~1~ and __T__~2~ mapping from becoming part of rout

Measurement of variation in the human ce
Measurement of variation in the human cerebral GABA level by in vivo MEGA-editing proton MR spectroscopy using a clinical 3 T instrument and its dependence on brain region and the female menstrual cycle
✍ Masafumi Harada; Hitoshi Kubo; Ayumi Nose; Hiromu Nishitani; Tsuyoshi Matsuda πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 296 KB πŸ‘ 2 views

## Abstract The objectives of this study were to examine the reproducibility of the MEGA‐editing J‐difference technique and to determine the normal variation in the γ‐aminobutyric acid (GABA) level depending on the cerebral region and its fluctuation according to the menstrual cycle as baseline dat