Essential oils were obtained by hydrodistillation of leaves, inflorescences and fruits of Vitex ugnus-castus L. (Verbenaceae). Yields ranged from 0.8 to 1.8% on dry weight basis. Eighty-five compounds were identified by GC-MS. The ratio of hydrocarbon : oxygen-containing components was nearly 1:l. 1
Vitex agnus castus L.,—traditional drug and actual indications
✍ Scribed by Karl Peter Odenthal
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 60 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
There is a long tradition for the use of different preparations of drugs of Vitex agnus castus in complementary medicine in Europe. The indications in disorders of the female sexual cycle have been confirmed by experimental and clinical results. The activity of hitherto unidentified constituents of the ethanol seed extract could be localized within the pituitary-gonadal axis. Research in pituitary cell assays further elucidated a dopaminergic inhibition of prolactin synthesis and/or release. The effective administration of ethanol seed extracts against mastodynia and symptoms related to female cycle disorders with concomitant hyperprolactinaemia has been documented and awaits further establishment.
📜 SIMILAR VOLUMES
The essential oils of fresh leaves, ¯owers and fruits of Vitex agnus-castus L., growing in north Brazil, were obtained by hydrodistillation and their volatile constituents were identi®ed by GC±MS. The most abundant constituents found were 1,8-cineole, (E)-b-farnesene, sabinene, a-pinene, a-terpenyl