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Viscoelastic properties of pharmaceutical semisolids I: Ointment bases

โœ Scribed by S. S. Davis

Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
633 KB
Volume
58
Category
Article
ISSN
0022-3549

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โœฆ Synopsis

The rheological evaluation of semisolids by continuous shear methods is limited in its application. However if materials are viscoelastic, their properties can be assessed in creep testing where fundamental parameters are provided and rheological behavior can be represented by mechanical models. Measurements have been made on a number of ointment bases over a range of temperature. The addition of small quantities of complex materials to paraffin ointment bases changes their behavior from elastic to viscoelastic. As many of the materials show a characteristic change in viscoelastic spectrum with temperature it is hoped that creep testing will provide a suitable method for the correct rheological evaluation of many important materials.

Keyphrases

Viscoelastic properties-ointment bases 0 Ointment bases-creep testing 0 Creep compliance-ointment 0 Temperature effect-viscoelastic properties 0 Shear, continuous, creep-ointment viscoelasticity

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