Hepatitis C virus (HCV)-RNA in sera of patients with viral hepatitis C is supposed to be included, at least partially, into HCV particles. We found that the density of HCV-RNA-carrying material was variable, as determined by sucrose gradient density centrifugation (1.03-1.20g/cm3). In some of the se
Virolytic action of lipoprotein lipase on hepatitis C virus in human sera
β Scribed by Reiner Thomssen; Sigrid Bonk
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 108 KB
- Volume
- 191
- Category
- Article
- ISSN
- 0300-8584
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Heterogeneities in the density of hepatitis C virus RNA-carrying material (HCV-RNA-CM) found in human sera (1.03-1.20g/cm 3) are attributed to the binding of low-density lipoproteins and/or of IgG. In some sera HCV-RNA-CM seems to be nearly totally bound to 13-1ipoproteins and cannot be precipitated
Serum samples (1,428) from 1,149 patients with chronic liver diseases and polfiransfused subjects were tested for antibody to hepatitis C virus by first-generation enzyme immunoassays. Antibody to hepatitis C virus was detected in 87% of patients with transfusion-related chronic non-A, non-B hepatit
## Abstract Conformational Bβcell epitopes on the HCV E2 protein recognized by human antibodies were characterized by the use of a peptide mimotope named K1. K1 was identified by two HCV antiβE2 monoclonal antibodies (mAbs) following selection and purification of phage clones containing a 15βmer ra