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Vincristine-induced myocardial infarction

✍ Scribed by Eugen M. Mandel; Uri Lewinskimd; Professor Meir Djaldetti

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
986 KB
Volume
36
Category
Article
ISSN
0008-543X

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✦ Synopsis

Abstract

A patient with lymphosarcoma treated with weekly injections of vincristine developed an acute myocardial infarction immediately after the second injection of vincristine. After he recovered from the infarction, the treatment was continued and he developed an additional myocardial infarction. In vivo and in vitro studies have not revealed any effect of vincristine on the clotting mechanism. The possible causes for the association of vincristine‐treated lymphoma and myocardial infarction are discussed. Canceri 36:1979–1982, 01975

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