✦ LIBER ✦

Vincristine-induced myocardial infarction

✍ Scribed by Eugen M. Mandel; Uri Lewinskimd; Professor Meir Djaldetti

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 986 KB
Volume: 36
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.2820360608

No coin nor oath required. For personal study only.

✦ Synopsis

A patient with lymphosarcoma treated with weekly injections of vincristine developed an acute myocardial infarction immediately after the second injection of vincristine. After he recovered from the infarction, the treatment was continued and he developed an additional myocardial infarction. I n vivo and in vitro studies have not revealed any effect of vincristine on the clotting mechanism. T h e possible causes for the association of vincristine-treated lymphoma and myocardial infarction are discussed.

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