Vibrational Raman optical activity study of d-glucose

✍ Scribed by Alasdair F. Bell; Laurence D. Barron; Lutz Hecht

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 989 KB
• Volume: 257
• Category: Article
• ISSN: 0008-6215
• DOI: 10.1016/0008-6215(94)84104-7

✦ Synopsis

Vibrational Raman optical activity (ROA) spectra in back-scattering from 600 to 1600 cm-l of D-glucose, D-glucose-l-d, o-glucose-6,6-d,, o-glucose-o-d,, 5-thio-D-glucose, and D-glucosamine hydrochloride are reported. Prominent signals for o-glucose appear in the region above -950 cm-' and can be subdivided into a fingerprint region from -950 to -1200 cm-', and a CH, and C-O-H deformations region above -1200 cm-'. In the fingerprint region, ROA signals which reflect the relative orientation of substituents originate primarily in skeletal C-C and C-O stretch coordinates: C-O-H deformation coordinates also contribute to the parent Raman band intensity but not to the ROA intensity. In the CH, and C-O-H deformations region, negative and positive ROA bands appear at -1220 and -1260 cm-', which may be attributed to the gauche-gauche and gauche-trans

rotamers of the exocyclic hydroxymethyl group, respectively. The -1260 cm-' ROA signal also reflects the anomeric configuration since only the p anomer generates an ROA signal at this wavenumber.