Content: Cover; Contents; Foreword; Abbreviations; Preface; Key to Symbols; 1 An Overview of the Immune System: Innate and Adaptive Immunity and the Inflammatory Response; Introduction; History of immunology; The immune system: an overview; The evolution of the immune system; Key points; 2 Antigens and Antibodies; Introduction; Antigens; Antibodies; Immunoglobulin classes; Antigen-antibody interaction; Key points; 3 The Complement System; Introduction; The classical and lectin pathways; The alternative pathway; The terminal pathway; Biological consequences of complement activation. Tests of complement functionKey points; 4 Serological Testing; Introduction; Serological tests; Key points; 5 Cells and Tissues of the Immune System; Introduction; Primary lymphoid tissue; Secondary lymphoid tissue; Lymphocytes; Distinguishing between immune cells; Lymphocyte recirculation; The common mucosal system; Key points; 6 The Major Histocompatibility Complex; Introduction; Graft rejection; Major histocompatibility antigens; The major histocompatibility complex; The inheritance of MHC; MHC disease associations; Other applications of tissue typing; Key points. Activation of the B lymphocyteB-cell receptor diversity; The immunoglobulin class switch; Affinity maturation; Kinetics of the humoral immune response; B1 and B2 lymphocytes; Memory B lymphocytes; Monoclonal antibodies; Key points; 10 Testing of Cellular Immune Function; Introduction; Lymphocyte stimulation tests; Tests of cytotoxic function; Tests of phagocytic cell function; Key points; 11 Immune Suppression; Introduction; Antigen usage; Antibody-mediated suppression; The neuroendocrine-immunological loop; Regulatory (suppressor) T lymphocytes; Key points; 12 Hypersensitivity Mechanisms. IntroductionThe Gell and Coombs classification of hypersensitivity; Type I hypersensitivity; Type II hypersensitivity; Type III hypersensitivity; Type IV hypersensitivity; Key points; 13 The Immune Response to Infectious Agents; Introduction; The immune response to viral infection; The immune response to bacterial infection; The immune response to helminth infection; The immune response to protozoal infection; The immune response to fungal infection; Key points; 14 Cancer Immunology and Immune System Neoplasia; Introduction; Tumour antigens; The antitumour immune response.
Abstract:
Accompanies and complements the teaching of immunology within the veterinary curriculum. Covers large and small animals, and provides clear learning objectives focusing on immunological principles while applying them to the disease process and to clinical practice. Case based and illustrated throughout in colour. Read more...