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Versatile synthesis of oligodeoxyribonucleotide–oligospermine conjugates

✍ Scribed by Voirin, Emilie; Behr, Jean-Paul; Kotera, Mitsuharu

Book ID
109946176
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
263 KB
Volume
2
Category
Article
ISSN
1750-2799

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Any oligodeoxyribonucleotide triester block with a 3' aryl phosphate end can be protected by condensing its phosphodiester N4,~3',~5'-tribensoylcytidine. terminal with the 2'-hydroxyl group of As the final step in deprotection of the modified block, mild treatment with Pb\* ion cleaves the new 3'-2