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Improved synthesis of oligodeoxyribonucleotides

✍ Scribed by Klaus-Peter Stengele; Wolfgang Pfleiderer


Book ID
103403566
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
210 KB
Volume
31
Category
Article
ISSN
0040-4039

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Improved Synthesis of Oligodeoxyribonucl
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## Abstract The synthesis of oligodeoxyribonucleotides on a cross‐linked polystyrene solid support utilizing stable mono‐ and dinucleotide phosphotriester building blocks is presented. The use of __O__^6^[2‐(__p__‐nitrophenyl)ethyl]‐2′‐deoxyguanosine derivatives yields cleaner DNA fragments by supp