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VEGF-Induced Activation of Phosphoinositide 3-Kinase Is Dependent on Focal Adhesion Kinase

✍ Scribed by Jian Hua Qi; Lena Claesson-Welsh


Book ID
115603892
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
403 KB
Volume
263
Category
Article
ISSN
0014-4827

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## Abstract Many G protein coupled receptors (GPCRs) cause phosphorylation of MAP kinases through transactivation of the epidermal growth factor receptor (EGF‐R), leading to increased cell survival and growth, motility, and migration. Phosphoinositide 3‐kinase (PI3K) is one of the important cell su