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Phosphoinositide 3-kinase-dependent activation of Rac

✍ Scribed by Heidi C.E. Welch; W.John Coadwell; Len R. Stephens; Phillip T. Hawkins

Book ID
117105414
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
220 KB
Volume
546
Category
Article
ISSN
0014-5793

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## Abstract Many G protein coupled receptors (GPCRs) cause phosphorylation of MAP kinases through transactivation of the epidermal growth factor receptor (EGF‐R), leading to increased cell survival and growth, motility, and migration. Phosphoinositide 3‐kinase (PI3K) is one of the important cell su