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Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells

✍ Scribed by Matthew K Henry; Dipali Nimbalkar; Raymond J Hohl; Frederick W Quelle


Book ID
116981091
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
547 KB
Volume
299
Category
Article
ISSN
0014-4827

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## Abstract The effects of P2Y2 purinoceptor activation on c‐Fos expression and the signaling pathways evoked by extracellular ATP/UTP in HeLa cells were investigated. We found that P2Y2 activation induced c‐Fos protein and phosphorylated the extracellular signal‐regulated kinases 1 and 2 (ERK1/2).