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Variations in the serotonin transporter genotype and potential endophenotypes for affective disorder

✍ Scribed by M. Vinberg; E. Mellerup; P.K. Andersen; B. Bennike; L.V. Kessing

Book ID
118439827
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
64 KB
Volume
23
Category
Article
ISSN
0924-9338

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The serotonin transporter knockout (SERT(-/-)) mouse, generated in 1998, was followed by the SERT(-/-) rat, developed in 2006. The availability of SERT(-/-) rodents creates the unique possibility to study the conservation of gene function across species. Here we summarize SERT(-/-) mouse and rat dat