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Variations in the detection of ZAP-70 in chronic lymphocytic leukemia: Comparison with IgVH mutation analysis

✍ Scribed by M. R. Sheikholeslami; I. Jilani; M. Keating; J. Uyeji; K. Chen; H. Kantarjian; S. O'Brien; F. Giles; M. Albitar

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
560 KB
Volume
70B
Category
Article
ISSN
1552-4949

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## Abstract ## Background: Expression of T cell specific zeta‐associated protein 70 (ZAP‐70) by B‐cell chronic lymphocytic leukemia (B‐CLL) cells, as investigated by flow cytometry, has both prognostic relevance and predictive power as surrogate for immunoglobulin heavy chain variable region (IgV~