Variation in oncogenic and transforming potential of PARA (defective SV40)-adenovirus 7
β Scribed by R. Duff; P. Knight; F. Rapp
- Book ID
- 119008536
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- English
- Weight
- 500 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0042-6822
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## Abstract PARA (defective SV40) was transcapsidated from adenovirus type 7 to the highly oncogenic Huie strain of adenovirus type 12. This transfer of PARA to adenovirus 12 was found to hasten the appearance of SV40βtype tumors in hamsters inoculated as newborns; the tumors induced by the PARAβad
## Abstract ME1 C9, a cloned line of mouse embryo cells, transformed by SV40 in vitro, and its more malignant progeny, ME1 C9βV15, derived from a tumor of the 15th consecutive passage of ME1 C9 in vivo, were compared as regards immunogenicity and immunosensitivity in syngeneic CBA mice. A threshold