## Abstract The properties of hamster cells containing SV40 tumor (T) antigen in the cytoplasm, rather than the nucleus, were determined. Eight cell lines were established from eight tumors induced by hamster embryo fibroblasts transformed __in vitro__ by PARA (2cT)โadenovirus 7. Six cell lines con
Transformation of hamster cells by variants of PARA- adenovirus 7 able to induce SV40 tumor antigen in the cytoplasm
โ Scribed by Duff, Ronald; Rapp, Fred; Butel, Janet S.
- Book ID
- 122644076
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- English
- Weight
- 219 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0042-6822
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A clone of hamster fibroblasts tramformed by SV40 virus (TSVKCL,) induced antibodies in hamsters against new antigenic constituents not present in the untransformed fibroblasts. The antibodies in the immune sera against histocompatibility antigens and those against nuclear T antigen were absorbed. T
## Abstract The immunogenicity of the SV40 tumorโspecific transplantation antigen (TSTA) on cells, cell particulates and solubilized membranes was studied in mice and in Syrian hamsters. Immunizations were done with various concentrations of tissueโcultureโpassaged, nonโvirusโreleasing transformed