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Variability in the stereoselective disposition of ibuprofen in patients with rheumatoid arthritis.

โœ Scribed by G Geisslinger; KP Stock; D Loew; GL Bach; K Brune

Book ID
117945481
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
907 KB
Volume
35
Category
Article
ISSN
0306-5251

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## Abstract In a 4โ€week doubleโ€blind trial in 41 patients with rheumatoid arthritis, ibuprofen (Motrinยฎ) decreased the swollen joint count significantly at a dosage level of 2400 mg/day, but not at 1200 mg/day. Ibuprofen probably does have antiinflammatory effects in man, but only at higher dosages