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Variability in the developmental toxicity of bropirimine with the day of administration

โœ Scribed by Marks, Thomas A. ;Black, Daniel L. ;Terry, Roger D. ;Branstetter, Daniel G. ;Kirton, Kenneth T.

Book ID
112219078
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
948 KB
Volume
42
Category
Article
ISSN
0040-3709

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The developmental effect of the topoisomerase inhibitor, etoposide, was investigated in pregnant rabbits given intravenous doses during early organogenesis. Does received 0, 0.25, 0.5, 1, or 2 mg/kg/day on days 7 through 9 of gestation. Fetal parameters were evaluated on day 28 of gestation. Live fe