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Van Buchem Disease (Hyperostosis Corticalis Generalisata) Maps to Chromosome 17q12-q21

✍ Scribed by Wim Van Hul; Wendy Balemans; Els Van Hul; Frederik G. Dikkers; Henk Obee; Robert J. Stokroos; Peter Hildering; Filip Vanhoenacker; Guy Van Camp; Patrick J. Willems


Book ID
117852296
Publisher
American Society of Human Genetics
Year
1998
Tongue
English
Weight
736 KB
Volume
62
Category
Article
ISSN
0002-9297

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## Abstract Van Buchem disease is an autosomal recessive sclerosing bone dysplasia characterized by skeletal hyperostosis, overgrowth of the mandible, and a liability to entrapment of the seventh and eighth cranial nerves. The genetic determinant maps to chromosome 17q12‐q21. We refined the critica