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Localization of the Gene for Sclerosteosis to the van Buchem Disease–Gene Region on Chromosome 17q12–q21

✍ Scribed by Wendy Balemans; Jenneke Van Den Ende; Auristela Freire Paes-Alves; Frederik G. Dikkers; Patrick J. Willems; Filip Vanhoenacker; Neli de Almeida-Melo; Cristiane Freire Alves; Constantine A. Stratakis; Suvimol C. Hill; Wim Van Hul

Book ID
117852855
Publisher
American Society of Human Genetics
Year
1999
Tongue
English
Weight
667 KB
Volume
64
Category
Article
ISSN
0002-9297

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## Abstract Van Buchem disease is an autosomal recessive sclerosing bone dysplasia characterized by skeletal hyperostosis, overgrowth of the mandible, and a liability to entrapment of the seventh and eighth cranial nerves. The genetic determinant maps to chromosome 17q12‐q21. We refined the critica