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The Human Insulin-like Growth Factor-Binding Protein 4 Gene Maps to Chromosome Region 17q12-q21.1 and Is Close to the Gene for Hereditary Breast-Ovarian Cancer

✍ Scribed by Patricia Tonin; Ewa Ehrenborg; Gilbert Lenoir; Jean Feunteun; Henry Lynch; Kenneth Morgan; Henric Zazzi; Anne Vivier; Michael Pollak; Hung Huynh; Holgar Luthman; Catharina Larsson; Steven Narod

Book ID: 115611851
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 196 KB
Volume: 18
Category: Article
ISSN: 0888-7543
DOI: 10.1006/geno.1993.1487

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Localization of the human insulin-like growth-factor-binding protein 4 gene to chromosomal region 17q12–21.1

✍ Svetlana Bajalica; Susanne V. Allander; Ewa Ehrenborg; Karen Brøndum-Nielsen; Ho 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 983 KB

Insulin-like growth-factor-binding proteins (IGFBPs) constitute a family of structurally related proteins that specifically bind insulin-like growth factors and modulate their functions. In this study, the chromosomal localization was determined for the gene encoding IGFBP4, i.e. inhibitory-IGFBP. A