Valproic Acid Promotes Neurite Outgrowth in PC12 Cells independent from Regulation of the Survival of Motoneuron Protein
β Scribed by Jeroen van Bergeijk; Kirsten Haastert; Claudia Grothe; Peter Claus
- Book ID
- 111368284
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 115 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1747-0277
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## Abstract Binding of integrins to proteins of the extracellular matrix (ECM) provides structural and signaling information for biological processes such as cell proliferation, migration, neurite outgrowth, and differentiation. Integrins represent a family of heterodimeric transmembrane cell surfa
A combined assay to measure neurite outgrowth and B-50/GAP-43 levels in PC12 cells is reported. During NGF-induced neuritogenesis, B-50/GAP-43 expression was monitored by enzyme-linked immunosorbent assay (ELISA). Neurite outgrowth was quantified at the same time by the use of video image analysis.