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Depletion of a fatty acid-binding protein impairs neurite outgrowth in PC12 cells

✍ Scribed by Gregory W Allen; Jo-Wen Liu; Marino De León

Book ID
117385452
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
741 KB
Volume
76
Category
Article
ISSN
0169-328X

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The effects of inhibition of glycosylation on nerve growth factor (NGF) binding and neurite outgrowth response of PC12 cells have been examined. Exposure to tunicamycin (1-10 pgiml) for 24-36 hr eliminates the rapidly dissociating component of NGF binding and decreases the proportion of PC12 cells c