๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Valproic acid in epilepsy: Clinical and pharmacological effects

โœ Scribed by Richard H. Mattson; Joyce A. Cramer; Peter D. Williamson; Robert A. Novelly


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
580 KB
Volume
3
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Effects of adjunct valproic acid on clin
โœ Abigail L. Larrison; Shelly L. Babin; Yuan Xing; Saumil S. Patel; Adel A. Wassef ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 265 KB

## Objective Valproic acid (VPA) has been suggested as a potential adjunct therapy in schizophrenia for the treatment of clinical symptoms and cognitive deficits. Here, we investigate the effects of VPA on clinical symptoms and saccadic eye movements while controlling for multiple medication effect

Choleretic effect of valproic acid in th
โœ John B. Watkins; Curtis D. Klaassen ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 724 KB

Valproic acid (WA) is an anticonvulsant agent which produced marked choleresis in the rat. Bile flow rate increased from 50 to 60 pl per min per kg to 120 to 145 p1 per min per kg immediately after i.v. injection of VPA (37.5 to 150 mg per kg; 2 ml per kg) in male Sprague-Dawley rats. The duration o

The Hepatotoxicity of Valproic Acid and
โœ G. Richard Granneman; Shyh-Ing Wang; James W. Kesterson; Joseph M. Machinist ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 685 KB

The role of metabolites in valproic acid (VPA)-associated hepatotoxicity was studied in rats. The most steatogenic mono-unsaturated metabolite, 4-en-VPA, caused the greatest changes in indicators of beta-oxidation inhibition (dicarboxylic aciduria, beta-hydroxybutyrate reduction); however, the bioch