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ChemInform Abstract: Synthesis and Pharmacological Evaluation of Prodrugs of Valproic Acid.

✍ Scribed by N. Bodor; S. Chin Moon; L. Bruno-Blanch

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
31
Category
Article
ISSN
0931-7597

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Pharmacokinetic analysis and anticonvuls
Pharmacokinetic analysis and anticonvulsant activity of two polyesteric prodrugs of valproic acid
✍ Salim Hadad; Tom B. Vree; Eppo Van Der Kleijn; Meir Bialer πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 464 KB πŸ‘ 2 views

## Abstract The pharmacokinetics of the following two polyesteric prodrugs of valproic acid (VPA) have been investigated: 1,4‐butanediol divaiproate (BDV) and glyceryl trivalproate (GTV). In addition, the anticonvulsant activity of these compounds has been evaluated and compared to that of VPA and