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Validating a rapid, real-time, PCR-based direct mutation detection assay for preimplantation genetic diagnosis

✍ Scribed by Chen, Hsin-Fu; Chang, Shun-Ping; Wu, Sheng-Hai; Lin, Wen-Hsiang; Lee, Yi-Chung; Ni, Yen-Hsuan; Chen, Chi-An; Ma, Gwo-Chin; Ginsberg, Norman A.; You, En-Min; Tsai, Feng-Po; Chen, Ming

Book ID: 125824473
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 668 KB
Volume: 548
Category: Article
ISSN: 0378-1119
DOI: 10.1016/j.gene.2014.07.039

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## Communicated by Stylianos Antonarakis Sickle-cell and b-thalassemia syndromes are priority genetic diseases for prevention programs involving population screening with the option of prenatal diagnosis for carrier couples. Preimplantation genetic diagnosis (PGD) represents a specialized alternat