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Rapid real-time PCR assay for detection of MPL W515L mutation in patients with chronic myeloproliferative disorders

✍ Scribed by M. GHADERI; O. STRÖMBERG; A. PORWIT


Book ID
114897822
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
253 KB
Volume
32
Category
Article
ISSN
1751-5521

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MPL W515L/K mutations in 343 Chinese adu
✍ Guo-Rui Ruan; Bin Jiang; Ling-Di Li; Ji-Hong Niu; Jin-Lan Li; Min Xie; Ya-Zhen Q 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 278 KB

## Abstract Acquired mutations in the juxtamembrane region of __MPL__ (W515L or W515K), the receptor for thrombopoietin, have been reported in patients with primary essential thrombocythemia (ET) or primary myelofibrosis (PMF). The mutations were detected by the newly developed real‐time quantitati