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UV-light-induced conversion and aggregation of prion proteins

✍ Scribed by Lars Redecke; Stephan Binder; Mohammed I.Y. Elmallah; Rebecca Broadbent; Claudia Tilkorn; Benjamin Schulz; Patrick May; Arne Goos; Andreas Eich; Michael Rübhausen; Christian Betzel


Book ID
113630830
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
851 KB
Volume
46
Category
Article
ISSN
0891-5849

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Prior to delivery to the patient, protein pharmaceuticals often come in contact with a variety of surfaces (e.g., syringes and stoppers), which are treated to facilitate processing or to inhibit protein binding. One such coating, silicone oil, has previously been implicated in the induction of prote